The Westlake Meta4D Lab is an interdisciplinary, collaborative research laboratory aiming to push the limit in our understanding about the role of metabolism in human diseases. Our research focuses on three major goals:
Improve our understanding about metabolic regulation at cellular and subcellular levels, and systematically identify the metabolic and lipid components defining key cell-types and cell-states in the human body
Uncover key metabolic events underlying the progression of major human diseases including cancer, neurodegeneration and metabolic diseases.
Advance our technological capabilities in probing metabolite abundances and activities of metabolic pathways in vivo
The Westlake Meta4D Lab is equipped with cutting-edge instruments for metabolic analysis, including Mass Spectroscopy Imaging, High-resolution Metabolomics and Lipidomics, Raman Spectroscopy. Research at Meta4D lab will also benefit from the excellent core facilities and platforms at the School of Life Sciences and across Westlake University, spanning from high-throughput chemical screening, super-resolution imaging, genomics and bioinformatics, to multiple cryo-EM for structural analysis of macromolecules.